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Chelsea Lately’s series finale details

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E!’s Chelsea Lately wraps its seven-year run this Tuesday.

Chelsea Handler will be joined by some of her famous friends to mark the occasion, including best-friend Jennifer Aniston, Sandra Bullock and even her former flame 50 Cent! Yes – 50 Cent will perform with G Unit and reminisce with Chelsea.

The hour-long finale will be broadcast live from the famed Stage 1 at Universal Studios in Los Angeles and will include a musical number featuring Justin Theroux, Ben Falcone, Melissa McCarthy, Joe Manganiello, Leah Remini, Selena Gomez, Gerard Butler, Minnie Driver and Kristen Chenoweth, Trace Adkins, Avril Lavigne, James Van Der Beek, Rachel Bilson, Mary McCormack, Kelly Osbourne, Helen Hunt, Sheila E, Richard Marx, Kathryn Hahn, Johnny Knoxville, Tim Gunn, Anna Faris, Gabriel Iglesias, Chloe Grace Moretz, Buzz Aldrin, Sammy Hagar, Vanessa Hudgens, Sophia Bush, Jenny & Jason Biggs, Allison Janney, Alessandra Ambrosio, Kathy Griffin, Kevin Nealon, Marlee Matlin and David Hasselhoff.

Chelsea Handler announced plans to end her talk show earlier this year and signed an exclusive deal to star in a new talk show with Netflix this past June. While Handler’s new show won’t premiere on Netflix until early 2016, look for the comedienne’s first of five comedy specials to premiere on the streaming platform on Friday, October 20.

The series finale of Chelsea Lately will air Tuesday, August 26 at 11:00 p.m. ET on E!

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